منابع مشابه
A mathematical model for dorsal closure.
During embryogenesis, drosophila embryos undergo epithelial folding and unfolding, which leads to a hole in the dorsal epidermis, transiently covered by an extraembryonic tissue called the amnioserosa. Dorsal closure (DC) consists of the migration of lateral epidermis towards the midline, covering the amnioserosa. It has been extensively studied since numerous physical mechanisms and signaling ...
متن کاملQuantifying dorsal closure in three dimensions
Dorsal closure is an essential stage of Drosophila embryogenesis and is a powerful model system for morphogenesis, wound healing, and tissue biomechanics. During closure, two flanks of lateral epidermis close an eye-shaped dorsal opening that is filled with amnioserosa. The two flanks of lateral epidermis are zipped together at each canthus ("corner" of the eye). Actomyosin-rich purse strings a...
متن کاملSimulation of Pedestrian Dynamics with Macroscopic and Microscopic Mathematical Models
Here, we collect two parts of a research project on the pedestrian flow modeling. Rapid growth in the volume of public transport and the need for its reasonable, efficient planning have made the description and modeling of transport and pedestrian behaviors as important research topics in the past twenty years. First, we present a macroscopic model for the pedestrian flow based on continuum mec...
متن کاملModulation of Morphogenesis by Egfr during Dorsal Closure in Drosophila
During Drosophila embryogenesis the process of dorsal closure (DC) results in continuity of the embryonic epidermis, and DC is well recognized as a model system for the analysis of epithelial morphogenesis as well as wound healing. During DC the flanking lateral epidermal sheets stretch, align, and fuse along the dorsal midline, thereby sealing a hole in the epidermis occupied by an extra-embry...
متن کاملA cell-level biomechanical model of Drosophila dorsal closure.
We report a model describing the various stages of dorsal closure of Drosophila. Inspired by experimental observations, we represent the amnioserosa by 81 hexagonal cells that are coupled mechanically through the position of the nodes and the elastic forces on the edges. In addition, each cell has radial spokes representing actin filaments on which myosin motors can attach and exert contractile...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Progress in Biophysics and Molecular Biology
سال: 2018
ISSN: 0079-6107
DOI: 10.1016/j.pbiomolbio.2018.05.009